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Purified in vivo Grade Antibod

2025-03-20 来源:互联网

Leinco Technologies offers high-purity research-grade biosimilar antibodies with the same specifications as many therapeutic antibodies. Therapeutic antibodies are widely used for the treatment of diseases, including cancer and autoimmunity.

The Problem? Therapeutic-grade biologics are expensive, challenging to source, and only available in large quantities, making studies using these antibodies cost prohibited.

The Solution? Research-grade biosimilar antibodies are produced by recombinant technology using the variable region sequences of therapeutic antibodies, resulting in the same specificities as approved biologics. Leinco’s recombinant biosimilar antibodies are ideal research tools as they are fast, inexpensive, manufactured in an animal free facility and formulated in sterile PBS buffer, free of additives or preservatives.

Biosimilars Specifications

 Purity > 95% by SDS-PAGE and ≥ 98% monomer by analytical SEC  Endotoxin ≤ 0.5 EU/mg as determined by the LAL method

 Manufactured in an animal-free facility using protein-free, animal-origin-free cell culture media Ultra-low levels of leached protein A

Sterile filtered and formulated in Leinco’s in vivo grade PBS pH 7.2 containing no K or Ca, additives, preservatives, or carrier proteins

 Many research applications, including FC, ELISA, IHC, FA, PK and potency assays Pathogen tested (IMPACT1)

IDEXX IMPACT I (PCR-based) Mouse Pathogen Profile

Mycoplasma sp. Mouse adenovirus 1 (MAV1) Lactate dehydrogenase-elevating virus (LDEV)

Mycoplasma pulmonis Mouse adenovirus 2 (MAV2) Lymphocytic choriomeningitis virus (LCMV)

Sendai virus Murine norovirus (MNV) Hantaan Virus

Mouse hepatitis virus (MHV) Reovirus 3 (REO3) Mouse cytomegalovirus (mCMV)

Pneumonia virus of mice (PVM) Mouse rotavirus (EDIM) K virus

Minute virus of mice (MVM) Ectromelia virus Mouse thymic virus (MTV)

Mouse parvovirus (MPV) Polyomavirus Corynebacterium bovis

Theiler’s murine encephalomyelitis (TMEV) Mouse kidney parvovirus (MKPV) Corynebacterium sp.

Research-Grade Biosimilars

For FC, IHC, ELISA, and more!

Adalimumab

Anti-Human TNFα

LT100

LT105

Atezolizumab

Anti-Human PD-L1

LT1750

LT1755

Bevacizumab

Anti-Human VEGF

LT400

LT405

Cetuximab

Anti-Human EGFR

LT600

LT605

Mogamulizumab

Anti-Human CD194

LT1000

LT1005

Nivolumab

Anti-Human PD-1

LT1200

LT1205

Oxelumab

Anti-Human OX40L

LT1300

LT1305

Teplizumab

Anti-Human CD3

LT2100

LT2105

Ipilimumab

Anti-Human CTLA-4

LT1600

LT1605

Conjugates include enzyme-labeled Biotin and HRP & fluorescent-labeled APC, PE, and Dylight®.

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